Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
If 2017 was the year policymakers began to worry about the growth of the “precariat”, 2018 will be the year they try to do something about it.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
I wish you a happy New Year. All affection and best wishes to you and yours.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
SETTING: This house is on Modena Island, about 20 miles from downtown Savannah. According to the listing agent, the community is gated and has about 20 houses sited amid live oaks and saltwater marshes. Modena Island is a part of Skidaway Island, which has an oceanography research facility operated by the University of Georgia and a large state park.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
"Micro blogs and other new media give everyone a speaking platform. If you cannot face the criticism and cooperate with the public, you cannot work well." ZHAO BAIGE, NPC deputy and executive vice-president of the Red Cross Society of China
Trends and targets in antiviral phototherapy
It makes piggybacks more comfortable.
James Bond Themes 1. "Goldfinger" by Shirley Bassey
Only two people know the Oscars winners list and supervise the counting procedures - PwC tax adviser Martha Ruiz and Brian Cullinan an accountant.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
10. China watchers inthe United States will continue to postulate China’s declining growth rate inthe face of evidence that it is stable at over 7%. China will grow fasterin 2014 than in 2013.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
The 1.48 million people who qualified to take the exam marked an increase of 90,000 over last year, while the number of positions offered - 27,000 - remained almost the same.
ACE2 as a potential therapeutic target for pandemic COVID-19
Stand: Starbucks CEO Howard Schultz urged the end of government shutdown
But if the U.S. can avert that Washington-made crisis, the outlook for workers finding jobs is actually looking pretty good for next year. For one thing, the damage of superstorm Sandy will have to be repaired, meaning jobs in construction and retail. Businesses, meanwhile, which have held off investing and hiring because of uncertainty over the fiscal outlook, might finally open their wallets. That means more jobs, too.[qh]
Diagnostic technologies for COVID-19: a review
Though its campuses often steal the benefits spotlight -- with their outdoor sports facilities, free food and more -- there's a more morbid perk that should certainly be noted. If a U.S. Googler passes away while working for the tech giant, the employee's spouse or domestic partner receives 50% of the deceased's salary, no matter how long or short his tenure, every year for the next decade.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Strong in many categories, but without quite managing to be a front runner in any. Perhaps Timothee Chalamet's performance is its best chance of awards success.
SIZE: 5,003 square feet total
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
10.Fears of Another Tsunami
We learned about the lingering toll of this frightening epidemic.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
I am calling this the Wan Long prize, after the Chinese meat magnate who once uttered the clearest sentence ever spoken by a CEO: “What I do is kill pigs and sell meat.” Mr Wan will surely approve of my winner, a BNSF railway executive who told a conference: “We move stuff from one place to another.”
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
The Bloomberg soft commodities index has gained 21 per cent, compared with 24 per cent for industrial metals and 1.5 per cent for energy.
Influenza neuraminidase: A druggable target for natural products
One highlight of last year's box office was seven high-quality domestic films listed on the top 10 earners, including 'Monster Hunt', a live-action hybrid, and 'Monkey King: Hero is Back', a 3D animation based on the classic ancient story.
Today, the Financial Times reveals the fake gross domestic product data routinely released from many northern Chinese regions. There, solid alternative evidence suggests the authorities have “smoothed” the economic growth figures. They artificially boosted growth figures between 2012 and 2016, masking a real downturn, and last year covered up a genuine recovery.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The Caixin-Markit manufacturing purchasing managers’ index dipped to 50.8 in November, down from 51 in October and coming closer to the 50-point threshold that delineates expansion from contraction. A median forecast from economists polled by Reuters had predicted a fall to 50.9.
Movies in 2016 are going to be huge and there's going to be a lot of them. Some of the best movies coming in 2016 include,Batman vs Superman: Dawn of Justice, Captain America: Civil War, Fantastic Beasts and Where to Find Them, Finding Dory, Rogue One: A Star Wars Story, X-Men: Apocalypse, Independence Day: Resurgence, WarCraft and Suicide Squad.
The role of biosensors in the detection of emerging infectious diseases
The rest of the top 10 2016 highest-paid actresses are:
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Bingo! In fewer than 20 words it combined five previous years’ winners, only to say nothing at all. With a heavy heart, I award eBay my overall Golden Flannel Award for 2016.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Capsized ship righted
Prices at China's factory gates fell for a 34th consecutive month in December, pushed down by falling energy and commodity prices.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
"Some geniuses in the internet industry created miracles, but that does not tell the whole story," said Chen. "Business has its own rules. Before you start up, you have to know how to produce products, how to sell them, how to manage a company. Those lessons you cannot expect a fresh graduate to know."
Inhibition of SARS coronavirus helicase by bismuth complexes
At least 120 million American voters had been expected to cast votes in the race between the Democratic incumbent and Romney after a campaign focused on how to repair the ailing U.S. economy。
In early 2005, Stone and her co-founders Elisa Camahort Page and Jory Des Jardins noticed that there were countless women blogging, but mainstream media rarely linked to their posts. The trio decided to host a grassroots conference that year and attracted sponsors like Google and Yahoo. It quickly sold out and soon after, they launched BlogHer.com. The publishing platform turned blogging into a lucrative business for many women -- it paid $25 million to 5,000 of its bloggers between 2009 and 2012 -- and now reaches an audience of 92 million.
China's movie box office revenue rose 13.45 percent in 2017 to more than 55.9 billion yuan (8.6 billion U.S. dollars), with domestic films contributing 53.84 percent to the market, according to the State Administration of Press, Publication, Radio, Film and Television.
If you think Kevin Durant is scrawny now, just take a look at his tiny physique back when he played at Montrose Christian.
A number of nude photographs have been leaked online after several female students offered the photos in exchange for high-interest loans via an online lending platform.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The other two tweets from Obama that made the list were posted when he was leaving the office.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
David said: ‘It was wonderful, you couldn’t fault it. It was perfection.’
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
4. 《卡罗尔》(Carol)。这是托德·海因斯(Todd Haynes)第一次执导不由自己编剧的影片，编剧菲丽丝·奈吉(Phyllis Nagy)简化了派翠西亚·海史密斯(Patricia Highsmith)的小说原著，海因斯藉此再次证明，电影导演不必依靠拍自己亲自写的剧本才能成为伟大导演，这个真理却遭到许多雄心勃勃或功成名就的导演忽略。
通常冷静的分析师们早已习惯了汽车行业的缓慢增长，但是遇到特斯拉，他们就丢掉了一贯的谨慎。德意志银行（Deutsche Bank）的分析师罗德o拉切给该股设定了310美元的目标价格。无独有偶，摩根士丹利（Morgan Stanley）的分析师亚当o乔纳斯也将特斯拉的目标股价定为320美元，并称它是“世界上最重要的汽车公司”。
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Will Zimbabwe’s new leader hold — and win — fair elections
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
China hopes that the Asia-Pacific region will be one that enjoys order and stability, a region that is able to work out issues through consensus-building consultation, properly manage differences through dialogue and has the wisdom to resolve differences.
Two days ago here in Brazil, we were shocked when we spent some time with some children living on the streets. And this is what one child told us: "I wish I was rich and if I were, I would give all the street children food, clothes, medicine, shelter and love and affection." 在巴西，我被2天前见到的情景震惊了，那时我和当地的小孩在玩耍，其中一个小孩说：“我希望我能富裕起来，然后我会给这个街道所有的小孩饭吃，给他们衣服穿，医疗，住房和爱”。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Ranking third on our Top-Grossing list is Steve Carell. Despicable Me 2 was a huge hit this year, bringing in $919 million at the box office. Overall, the franchise has earned $1.4 billion at the box office worldwide and a third movie, Minions, is on the way. Carell also appeared this year in the small indie The Way Way Back and The Incredible Burt Wonderstone. The latter failed to earn back its production budget at the box office but we’re only looking at ticket sales here — the film put another $22.5 million in Carell’s column for 2013.
The relocation is also part of the integration plan for the Beijing-Tianjin-Hebei cluster, which aims to ease congestion in the capital and achieve more balanced development in the region.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
As the socialite arrived at Kylie Jenner's 19th birthday party in August she alighted her sports car in such a cack-handed (cack-legged, I suppose) way that meant that more was glimpsed than intended.
At a minimum, it is impossible for most people to get to work in the city, which affects the locus of several industries, including finance, advertising, healthcare and the arts. The city's transportation lines, bridges, and tunnels were shut down for nearly two days, and at the latest report, the subways may be down well into next week.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
The workers, who were part of a crew building a football stadium, were taken in the mainly Shi'ite Habibiya district in northeastern Baghdad.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
“不能再采取某些国家先行动，其他国家随后行动的策略，因为时间不多了，”奥斯陆国际气候与环境研究中心(Center for International Climate and Environmental Research)的科学家格伦·P·彼得斯(Glen P. Peters)说。他也参与了这些新数据的编制。“现在需要大家齐心协力。”
For democrats, the outburst of such primal emotions is disturbing because they are so hard to contain.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Star Wars: Rogue One is set to release on December 16, 2016.
The Caixin-sponsored series is based on a much smaller sample of private companies than the official PMI reading, which focuses on larger state enterprises, and tends to be more volatile.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
It can transport rows of seedlings in minutes. And can reduce planting time by 88 percent.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
And a few stopped to change a tire for an elderly French couple.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Although Facebook is blocked in China, Tencent has linked WeChat to Facebook, which means that users outside of China can use the service in conjunction with the world's most popular social network. That is a boon for WeChat in Southeast Asian countries like Indonesia, Thailand and the Philippines, which have large numbers of Facebook users. Tencent has offered WeChat in languages for all three markets.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
At the end of a politically charged ceremony in which Donald Trump was the subject of frequent jokes by host Jimmy Kimmel, Warren Beatty and Faye Dunaway announced that La La Land had won. But as the producers and cast of Damien Chazelle’s modern musical were on stage giving emotional thank you speeches, they were told that Moonlight was the real winner.
A facile assay for rapid detection of COVID-19 antibodies
“Airbnb is here to stay,” Mr. Gottsegen said. “Instead of fighting it, we should wrap our arms around it and make it better.”
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
"Last year, 1.2 million Chinese visited Australia. We anticipate this will grow during the China-Australia Year of Tourism and will continue to grow afterward."
Typically, he writes, analysts “see the root cause of emerging markets’ susceptibility to crises in weak institutions that make countries vulnerable to economic and financial instability.”
When a cup is placed on a dispenser, a magnet lifts to let beer flow in.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Stevens会演唱电影《以你的名字呼唤我》中《Mystery of Love》，以及Bernal, LaFourcade和 Miguel会合唱《寻梦环游记》中的歌曲《Remember Me》。
A 19-year-old girl, referred to as Guo Lingling (this may be a pseudonym), was allegedly struck and kicked repeatedly by her so-called instructors after failing to ask permission to go to the bathroom. An autopsy report showed she died from skull injuries and brain damage.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Xi Jinping and other leadershave made it clear that China is willing to accept a slower growth pace if thiswill allow for a more sustainable, consumer-driven expansion of its economy.Some prognosticators are quick to conclude that China’s economy will soonsignificantly slow down, especially because China’s economy has sputteredfollowing prior instances when the nation’s leaders have effected suchfundamental economic reforms (such as in 1978 and 1993).
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
There are a wide range of low-cost flights to Russia and transportation in the country is also easy with the Trans-Siberian Railway.
We think of the passage of NBA time in seasons, for obvious reasons. There's connection, a continuum. It's how we remember things that happen, in the course of a season of play. But there's some benefit to looking back at a calendar year, January 1 to December 31, and what we've learned in that process. After all, many say the "unofficial start" to the NBA season is Christmas, with the new year starting soon after. So here are the lessons we learned about the NBA in the year 2017.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
A retrospective section will include movies produced by the Shanghai studio Wenhua, a company founded in 1946 that ushered a new era of Chinese art-house films, Zhang said, giving viewers "a glimpse of Chinese cinematic culture and history".
Length-scale dependence of protein hydration-shell density
Any decision by China’s policymakers to begin selling down the country’s huge reserves would have a large impact on markets.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
While the FT online and full-time MBAs are not strictly comparable because the criteria used to judge them are slightly different, it is interesting to note that IE and Warwick Business School are among six schools to feature in both rankings.
About this collection
The clothespin dates back to the 1800s, but in 2016 it became "smart." Meet Peggy, the laundry peg that's supposed to "help you lighten the load" by telling you when the washer cycle is over and if the weather is nice enough to hang your clothes outside. The device connects to your phones and sends you alerts when the weather changes or when you need to remove your clothes.
1. Beyoncé “Beyoncé” (Parkwood Entertainment/Columbia) An ambush that landed after last year’s tabulations, Beyoncé's tour de force — a lustrous showcase of soulful dominion, sleek production, sensual abandon and feminist agency, not always in that order — kept its relevance during a long year swollen with distractions. The singing, like the attitude, is phenomenally assured yet full of nuance; the message is complicated but clear. It’s high-wire pop that refuses to pander.